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Novel pathway compendium analysis elucidates mechanism of pro-angiogenic synthetic small molecule

Motivation: Computational techniques have been applied to experimental datasets to identify drug mode-of-action. A shortcoming of existing approaches is the requirement of large reference databases of compound expression profiles. Here, we developed a new pathway-based compendium analysis that coupl...

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Detalhes bibliográficos
Main Authors: Wieghaus, Kristen A., Gianchandani, Erwin P., Paige, Mikell A., Brown, Milton L., Botchwey, Edward A., Papin, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562016/
https://ncbi.nlm.nih.gov/pubmed/18718940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn451
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