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Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores

Summary: In genetics, many evolutionary pathways can be modeled by the ordered accumulation of permanent changes. Mixture models of mutagenetic trees have been used to describe disease progression in cancer and in HIV. In cancer, progression is modeled by the accumulation of chromosomal gains and lo...

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Auteurs principaux: Bogojeska, Jasmina, Alexa, Adrian, Altmann, André, Lengauer, Thomas, Rahnenführer, Jörg
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562010/
https://ncbi.nlm.nih.gov/pubmed/18718947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn410
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