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Genetic Dissection of the Role of Catechol-O-Methyltransferase in Cognition and Stress Reactivity in Mice

The COMT (catechol-O-methyltransferase) gene has been linked to a spectrum of human phenotypes, including cognition, anxiety, pain sensitivity and psychosis. Doubts about its clinical impact exist, however, because of the complexity of human COMT polymorphism and clinical variability. We generated t...

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Main Authors: Papaleo, Francesco, Crawley, Jacqueline N., Song, Jian, Lipska, Barbara K., Pickel, Jim, Weinberger, Daniel R., Chen, Jingshan
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561993/
https://ncbi.nlm.nih.gov/pubmed/18753372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2077-08.2008
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