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11-cis and all-trans retinols can activate rod opsin: Rational design of the visual cycle

Rhodopsin is the photosensitive pigment in the rod photoreceptor cell. Upon absorption of a photon, the covalently bound 11-cis retinal isomerizes to the all-trans form enabling rhodopsin to activate transducin, its G protein. All-trans retinal is then released from the protein and reduced to all-tr...

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Autores principales: Kono, Masahiro, Goletz, Patrice W., Crouch, Rosalie K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561911/
https://ncbi.nlm.nih.gov/pubmed/18563917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800357b
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