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Induction Time Measurement of Barbital Tolerance in Mice Given Recurrent Subhypnotic Dosage of Barbital

A procedure designed to estimate the degree of development of neuronal tolerance to barbiturates is described. With this technique, it has been shown that a subhypnotic (125 mg/kg) peritoneal dose of barbital sodium, given twice daily, over the course of either five or 10 consecutive days, can produ...

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Autori principali: Risher, Debra L., Baccus, Anita L., Townsend, Settle W., Proctor, Charles D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1982
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561420/
https://ncbi.nlm.nih.gov/pubmed/7154102
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