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Role of Major NMDA or AMPA Receptor Subunits in MK-801 Potentiation of Ethanol Intoxication

BACKGROUND: The glutamate system plays a major role in mediating EtOH’s effects on brain and behavior, and is implicated in the pathophysiology of alcohol-related disorders. N-methyl-D-aspartate receptor (NMDAR) antagonists such as MK-801 (dizocilpine) interact with EtOH at the behavioral level, but...

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Détails bibliographiques
Auteurs principaux: Palachick, Benjamin, Chen, Yi-Chyan, Enoch, Abigail J., Karlsson, Rose-Marie, Mishina, Masayoshi, Holmes, Andrew
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561332/
https://ncbi.nlm.nih.gov/pubmed/18565157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00715.x
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