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Identification of functional domains of Clostridium septicum alpha toxin

Alpha toxin (AT) is the major virulence factor of Clostridium septicum that is a proteolytically activated pore-forming toxin belonging to the aerolysin-like family of toxins. AT is predicted to be a three-domain molecule based on functional and sequence similarity with aerolysin, for which the crys...

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Bibliographic Details
Main Authors: Melton-Witt, Jody A., Bentsen, Lori M., Tweten, Rodney K.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561313/
https://ncbi.nlm.nih.gov/pubmed/17128973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061334p
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