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Variation in the Major Surface Glycoprotein Genes in Pneumocystis jirovecii

The genome of Pneumocystis, which causes life-threatening pneumonia in immunosuppressed patients, contains a multi-copy gene family that encodes the major surface glycoprotein (Msg). Pneumocystis can vary the expressed Msg, presumably as a mechanism to avoid host immune responses. Analysis of 24 msg...

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Bibliographic Details
Main Authors: Kutty, Geetha, Maldarelli, Frank, Achaz, Guillaume, Kovacs, Joseph A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561252/
https://ncbi.nlm.nih.gov/pubmed/18627244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/590433
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