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MOLECULAR ALTERATIONS IN THE CEREBELLUM OF THE PLASMA MEMBRANE CALCIUM ATPASE 2 (PMCA2)-NULL MOUSE INDICATE ABNORMALITIES IN PURKINJE NEURONS
PMCA2, a major calcium pump, is expressed at particularly high levels in Purkinje neurons. Accordingly, PMCA2-null mice exhibit ataxia suggesting cerebellar pathology. It is not yet known how changes in PMCA2 expression or activity affect molecular pathways in Purkinje neurons. We now report that th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561181/ https://ncbi.nlm.nih.gov/pubmed/17150372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2006.10.010 |
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