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MOLECULAR ALTERATIONS IN THE CEREBELLUM OF THE PLASMA MEMBRANE CALCIUM ATPASE 2 (PMCA2)-NULL MOUSE INDICATE ABNORMALITIES IN PURKINJE NEURONS

PMCA2, a major calcium pump, is expressed at particularly high levels in Purkinje neurons. Accordingly, PMCA2-null mice exhibit ataxia suggesting cerebellar pathology. It is not yet known how changes in PMCA2 expression or activity affect molecular pathways in Purkinje neurons. We now report that th...

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Main Authors: Kurnellas, Michael P., Lee, Amanda K., Li, Hong, Deng, Longwen, Ehrlich, Debra J., Elkabes, Stella
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561181/
https://ncbi.nlm.nih.gov/pubmed/17150372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2006.10.010
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