Lipoic acid stimulates cAMP production via the EP2 and EP4 prostanoid receptors and inhibits IFN gamma synthesis and cellular cytotoxicity in NK cells

The antioxidant lipoic acid (LA) treats and prevents the animal model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE). In an effort to understand the therapeutic potential of LA in MS, we sought to define the cellular mechanisms that mediate the effects of LA on human nat...

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Main Authors: Salinthone, Sonemany, Schillace, Robynn V., Marracci, Gail H., Bourdette, Dennis N., Carr, Daniel W.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561179/
https://ncbi.nlm.nih.gov/pubmed/18562016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.05.003
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