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ROCK1 and LIMK2 Interact in Spread but Not Blebbing Cancer Cells
Cancer cells migrating within a 3D microenvironment are able to adopt either a mesenchymal or amoeboid mode of migration. Amoeboid migration is characterised by membrane blebbing that is dependent on the Rho effectors, ROCK1/2. We identify LIMK2 as the preferred substrate for ROCK1 but find that LIM...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561063/ https://ncbi.nlm.nih.gov/pubmed/18852895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003398 |
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