Separation of Hepatitis C genotype 4a into IgG-depleted and IgG-enriched fractions reveals a unique quasispecies profile

BACKGROUND: Hepatitis C virus (HCV) circulates in an infected individual as a heterogeneous mixture of closely related viruses called quasispecies. The E1/E2 region of the HCV genome is hypervariable (HVR1) and is targeted by the humoral immune system. Hepatitis C virions are found in two forms: ant...

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Main Authors: Moreau, Isabelle, O'Sullivan, Hilary, Murray, Caroline, Levis, John, Crosbie, Orla, Kenny-Walsh, Elizabeth, Fanning, Liam J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561023/
https://ncbi.nlm.nih.gov/pubmed/18811965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-103
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