The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

BACKGROUND: Altered Cl(- )homeostasis and GABAergic function are associated with nociceptive input hypersensitivity. This study investigated the role of two major intracellular Cl(- )regulatory proteins, Na(+)-K(+)-Cl(- )cotransporter 1 (NKCC1) and K(+)-Cl(- )cotransporter 2 (KCC2), in neuropathic p...

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Main Authors: Cramer, Samuel W, Baggott, Christopher, Cain, John, Tilghman, Jessica, Allcock, Bradley, Miranpuri, Gurwattan, Rajpal, Sharad, Sun, Dandan, Resnick, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561007/
https://ncbi.nlm.nih.gov/pubmed/18799000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-36
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