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Whole Blood Interferon-Gamma Responses to Mycobacterium tuberculosis Antigens in Young Household Contacts of Persons with Tuberculosis in Uganda

BACKGROUND: Due to immunologic immaturity, IFN-γ-producing T cell responses may be decreased in young children compared to adults, thus we hypothesized that IFN-γ responses to mycobacterial antigens in household contacts exposed to Mycobacterium tuberculosis (Mtb) would be impaired in young children...

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Autors principals: Lewinsohn, Deborah A., Zalwango, Sarah, Stein, Catherine M., Mayanja-Kizza, Harriet, Okwera, Alphonse, Boom, W. Henry, Mugerwa, Roy D., Whalen, Christopher C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2560997/
https://ncbi.nlm.nih.gov/pubmed/18923705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003407
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