Enhanced Detection of Low Abundance Human Plasma Proteins Using a Tandem IgY12-SuperMix Immunoaffinity Separation Strategy

The enormous dynamic range of human bodily fluid proteomes poses a significant challenge for current MS-based proteomics technologies as it makes it especially difficult to detect low abundance proteins in human biofluids such as blood plasma, which is an essential aspect for successful biomarker di...

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Bibliografiske detaljer
Main Authors: Qian, Wei-Jun, Kaleta, David T., Petritis, Brianne O., Jiang, Hongliang, Liu, Tao, Zhang, Xu, Mottaz, Heather M., Varnum, Susan M., Camp, David G., Huang, Lei, Fang, Xiangming, Zhang, Wei-Wei, Smith, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Methodologies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559934/
https://ncbi.nlm.nih.gov/pubmed/18632595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800008-MCP200
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