The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

Histone monoubiquitylation is implicated in critical regulatory processes. We explored the roles of histone H2B ubiquitylation in human cells by reducing the expression of hBRE1/RNF20, the major H2B-specific E3 ubiquitin ligase. While H2B ubiquitylation is broadly associated with transcribed genes,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shema, Efrat, Tirosh, Itay, Aylon, Yael, Huang, Jing, Ye, Chaoyang, Moskovits, Neta, Raver-Shapira, Nina, Minsky, Neri, Pirngruber, Judith, Tarcic, Gabi, Hublarova, Pavla, Moyal, Lilach, Gana-Weisz, Mali, Shiloh, Yosef, Yarden, Yossef, Johnsen, Steven A., Vojtesek, Borivoj, Berger, Shelley L., Oren, Moshe
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2008
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559905/
https://ncbi.nlm.nih.gov/pubmed/18832071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1703008
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires