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Histone deacetylase 3 is required for centromeric H3K4 deacetylation and sister chromatid cohesion
We describe here the role of histone deacetylase 3 (HDAC3) in sister chromatid cohesion and the deacetylation of histone H3 Lys 4 (H3K4) at the centromere. HDAC3 knockdown induced spindle assembly checkpoint activation and sister chromatid dissociation. The depletion of Polo-like kinase 1 (Plk1) or...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2559902/ https://ncbi.nlm.nih.gov/pubmed/18832068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.484108 |
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