HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells

Binding of the HIV envelope to the chemokine coreceptors triggers membrane fusion and signal transduction. The fusion process has been well characterized, yet the role of coreceptor signaling remains elusive. Here we describe a critical function of the chemokine coreceptor signaling in facilitating...

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Main Authors: Yoder, Alyson, Yu, Dongyang, Dong, Li, Iyer, Subashini R., Xu, Xuehua, Kelly, Jeremy, Liu, Juan, Wang, Weifeng, Vorster, Paul J., Agulto, Liane, Stephany, David A., Cooper, James N., Marsh, Jon W., Wu, Yuntao
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559857/
https://ncbi.nlm.nih.gov/pubmed/18775311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.036
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