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High-Copy Suppressor Analysis Reveals a Physical Interaction between Sec34p and Sec35p, a Protein Implicated in Vesicle Docking

A temperature-sensitive mutant, sec34-2, is defective in the late stages of endoplasmic reticulum (ER)-to-Golgi transport. A high-copy suppressor screen that uses the sec34-2 mutant has resulted in the identification of the SEC34 structural gene and a novel gene called GRP1. GRP1 encodes a previousl...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Dong-Wook, Sacher, Michael, Scarpa, Al, Quinn, Anne Marie, Ferro-Novick, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25597/
https://ncbi.nlm.nih.gov/pubmed/10512869
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