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Expression of the precore region of an avian hepatitis B virus is not required for viral replication.

The core-antigen-coding region of all hepadnaviruses is preceded by a short, in-phase open reading frame termed precore whose expression can give rise to core-antigen-related polypeptides. To explore the functional significance of precore expression in vivo, we introduced a frameshift mutation into...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Chang, C, Enders, G, Sprengel, R, Peters, N, Varmus, H E, Ganem, D
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3041052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.10.3322-3325.1987
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