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CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity.

We have shown in a murine model system for acute, lethal cytomegalovirus (CMV) disease in the immunocompromised natural host that control of virus multiplication in tissues, protection from virus-caused tissue destruction, and survival are mediated by virus-specific CD8+ CD4-T lymphocytes. Protectio...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Reddehase, M J, Mutter, W, Münch, K, Bühring, H J, Koszinowski, U H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3041033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.10.3102-3108.1987
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