Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture.

A full-length cDNA copy of an attenuated, cell culture-adapted hepatitis A virus (HAV HM-175/7 MK-5) genome was constructed in the PstI site of plasmid vector pBR322. Transfection of monkey kidney cells with this plasmid failed to induce the production of hepatitis A virus (HAV). The HAV cDNA was ex...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cohen, J I, Ticehurst, J R, Feinstone, S M, Rosenblum, B, Purcell, R H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3041024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.10.3035-3039.1987
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