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Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture.

A full-length cDNA copy of an attenuated, cell culture-adapted hepatitis A virus (HAV HM-175/7 MK-5) genome was constructed in the PstI site of plasmid vector pBR322. Transfection of monkey kidney cells with this plasmid failed to induce the production of hepatitis A virus (HAV). The HAV cDNA was ex...

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Bibliografiske detaljer
Main Authors: Cohen, J I, Ticehurst, J R, Feinstone, S M, Rosenblum, B, Purcell, R H
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC255877/
https://ncbi.nlm.nih.gov/pubmed/3041024
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