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Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells.

Moloney murine leukemia virus (M-MuLV) and M-MuLV-derived retroviral vectors are not expressed in early mouse embryos or in embryonal carcinoma cells. M-MuLV-derived mutants or M-MuLV-related variants which transduce the neomycin phosphotransferase gene can, however, induce drug resistance in embryo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weiher, H, Barklis, E, Ostertag, W, Jaenisch, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC255781/
https://ncbi.nlm.nih.gov/pubmed/3612950
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