Antiidiotype modulation of herpes simplex virus infection leading to increased pathogenicity.

Antiidiotype reagents that recognize idiotypic determinants associated with the combining site of monoclonal antibodies to herpes simplex virus type 2 ( HSV2 ) were used to manipulate the immune response to HSV2 in BALB/c mice. The injection of antiidiotype antibodies into mice before challenge with...

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Bibliographic Details
Main Authors: Kennedy, R C, Adler-Storthz, K, Burns, J W, Henkel, R D, Dreesman, G R
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC255759/
https://ncbi.nlm.nih.gov/pubmed/6202879
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