Virus-induced diabetes mellitus: mengovirus infects pancreatic beta cells in strains of mice resistant to the diabetogenic effect of encephalomyocarditis virus.

In mice, Mengovirus produces a fatal encephalitis. Plaque purification of the virus resulted in the isolation of a clone (Mengo- 2T ), which in addition to encephalitis caused diabetes. Microscopic examination of pancreases from infected mice revealed necrosis in the islets of Langerhans and infiltr...

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Detalhes bibliográficos
Main Authors: Yoon, J W, Morishima, T, McClintock, P R, Austin, M, Notkins, A L
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC255725/
https://ncbi.nlm.nih.gov/pubmed/6327999
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