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N-terminal deletion in the src gene of Rous sarcoma virus results in synthesis of a 45,000-Mr protein with mitogenic activity.

Expression of the v-src gene of Rous sarcoma virus in avian embryo neuroretina cells results in transformation and sustained proliferation of these normally resting cells. Transformed neuroretina cells are also tumorigenic upon inoculation into immunodeficient hosts. We have previously described con...

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Udgivet i:J Virol
Principais autores: Laugier, D, Marx, M, Barnier, J V, Poirier, F, Genvrin, P, Dezélée, P, Calothy, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037114/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.8.2523-2529.1987
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