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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Accumulation of myeloid-derived suppressor cells (MDSCs) associated with inhibition of dendritic cell (DC) differentiation is one of the major immunological abnormalities in cancer and leads to suppression of antitumor immune responses. The molecular mechanism of this phenomenon remains unclear. We...

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Detalhes bibliográficos
Main Authors: Cheng, Pingyan, Corzo, Cesar A., Luetteke, Noreen, Yu, Bin, Nagaraj, Srinivas, Bui, Marylin M., Ortiz, Myrna, Nacken, Wolfgang, Sorg, Clemens, Vogl, Thomas, Roth, Johannes, Gabrilovich, Dmitry I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556797/
https://ncbi.nlm.nih.gov/pubmed/18809714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080132
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