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Delayed protection by ESAT-6–specific effector CD4(+) T cells after airborne M. tuberculosis infection

Mycobacterium tuberculosis infection induces complex CD4 T cell responses that include T helper type 1 (Th1) cells and regulatory T cells. Although Th1 cells control infection, they are unable to fully eliminate M. tuberculosis, suggesting that Th1-mediated immunity is restrained from its full steri...

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Bibliografiske detaljer
Main Authors: Gallegos, Alena M., Pamer, Eric G., Glickman, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556792/
https://ncbi.nlm.nih.gov/pubmed/18779346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080353
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