Mast cell–expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis

Mast cells contribute importantly to both protective and pathological IgE-dependent immune responses. We show that the mast cell–expressed orphan serpentine receptor mCCRL2 is not required for expression of IgE-mediated mast cell–dependent passive cutaneous anaphylaxis but can enhance the tissue swe...

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Main Authors: Zabel, Brian A., Nakae, Susumu, Zúñiga, Luis, Kim, Ji-Yun, Ohyama, Takao, Alt, Carsten, Pan, Junliang, Suto, Hajime, Soler, Dulce, Allen, Samantha J., Handel, Tracy M., Song, Chang Ho, Galli, Stephen J., Butcher, Eugene C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556791/
https://ncbi.nlm.nih.gov/pubmed/18794339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080300
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