Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines

BACKGROUND: The clinical efficacy of camptothecin (CPT), a drug specifically targeting topoisomerase I (TopoI), is under evaluation for the treatment of malignant gliomas. Due to the high unresponsiveness of these tumours to chemotherapy, it would be very important to study the signalling network th...

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Bibliografiske detaljer
Main Authors: Morandi, Elena, Severini, Cinzia, Quercioli, Daniele, D'Ario, Giovanni, Perdichizzi, Stefania, Capri, Miriam, Farruggia, Giovanna, Mascolo, Maria Grazia, Horn, Wolfango, Vaccari, Monica, Serra, Roberto, Colacci, Annamaria, Silingardi, Paola
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556695/
https://ncbi.nlm.nih.gov/pubmed/18694480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-66
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