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Caldesmon Inhibits Nonmuscle Cell Contractility and Interferes with the Formation of Focal Adhesions

Caldesmon is known to inhibit the ATPase activity of actomyosin in a Ca(2+)–calmodulin-regulated manner. Although a nonmuscle isoform of caldesmon is widely expressed, its functional role has not yet been elucidated. We studied the effects of nonmuscle caldesmon on cellular contractility, actin cyto...

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Detalhes bibliográficos
Main Authors: Helfman, David M., Levy, Esther T., Berthier, Christine, Shtutman, Michael, Riveline, Daniel, Grosheva, Inna, Lachish-Zalait, Aurelie, Elbaum, Michael, Bershadsky, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25564/
https://ncbi.nlm.nih.gov/pubmed/10512853
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