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Meiotic Regulation of TPX2 Protein Levels Governs Cell Cycle Progression in Mouse Oocytes

Formation of female gametes requires acentriolar spindle assembly during meiosis. Mitotic spindles organize from centrosomes and via local activation of the RanGTPase on chromosomes. Vertebrate oocytes present a RanGTP gradient centred on chromatin at all stages of meiotic maturation. However, this...

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Detalhes bibliográficos
Main Authors: Brunet, Stéphane, Dumont, Julien, Lee, Karen W., Kinoshita, Kazuhisa, Hikal, Pascale, Gruss, Oliver J., Maro, Bernard, Verlhac, Marie-Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556383/
https://ncbi.nlm.nih.gov/pubmed/18833336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003338
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