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The return of the Scarlet Pimpernel: cobalamin in inflammation II — cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS
The up-regulation of transcobalamins [hitherto posited as indicating a central need for cobalamin (Cbl) in inflammation], whose expression, like inducible nitric oxide synthase (iNOS), is Sp1- and interferondependent, together with increased intracellular formation of glutathionylcobalamin (GSCbl),...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Informa Healthcare
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556189/ https://ncbi.nlm.nih.gov/pubmed/18836533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10520290701791839 |
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