A Single CD8(+) T Cell Epitope Sets the Long-Term Latent Load of a Murid Herpesvirus

The pathogenesis of persistent viral infections depends critically on long-term viral loads. Yet what determines these loads is largely unknown. Here, we show that a single CD8(+) T cell epitope sets the long-term latent load of a lymphotropic gamma-herpesvirus, Murid herpesvirus-4 (MuHV-4). The MuH...

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Bibliografiske detaljer
Main Authors: Marques, Sofia, Alenquer, Marta, Stevenson, Philip G., Simas, J. Pedro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556087/
https://ncbi.nlm.nih.gov/pubmed/18846211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000177
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