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Selective DNA Strand Scission with Binuclear Copper Complexes: Implications for an Active Cu(2)-O(2) Species

A homologous series of binuclear copper(II) complexes [Cu(II)(2)(Nn)(Y)(2)](2+) (1–3) (n = 3–5 and Y = (ClO(4))(−) or (NO(3))(−)) were studied to investigate the intermediate(s) responsible for selective DNA strand scission in the presence of MPA/O(2) (MPA = 3-mercaptopropanoic acid). While the N3 c...

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Hlavní autoři: Thyagarajan, Sunita, Murthy, N. N., Narducci Sarjeant, Amy A., Karlin, Kenneth D., Rokita, Steve E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556057/
https://ncbi.nlm.nih.gov/pubmed/16719480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja061014t
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