A role for tumour necrosis factor-α, complement C5 and interleukin-6 in the initiation and development of the mycobacterial cord factor trehalose 6,6′-dimycolate induced granulomatous response

Trehalose 6,6′-dimycolate (TDM) is a glycolipid component of the mycobacterial cell wall that causes immune responses in mice similar to Mycobacterium tuberculosis (MTB) infection, including granuloma formation with production of proinflammatory cytokines. The precise roles of tumour necrosis factor...

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Main Authors: Welsh, Kerry J., Abbott, April N., Hwang, Shen-An, Indrigo, Jessica, Armitige, Lisa Y., Blackburn, Michael R., Hunter, Robert L., Actor, Jeffrey K.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556040/
https://ncbi.nlm.nih.gov/pubmed/18524936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.2008/016923-0
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