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Negative Regulation of the Yeast ABC Transporter Ycf1p by Phosphorylation within Its N-terminal Extension

The yeast vacuolar membrane protein Ycf1p and its mammalian counterpart, MRP1, belong to the ABCC subfamily of ATP-binding cassette (ABC) transporters that rid cells of toxic endogenous and xenobiotic compounds. Like most members of the ABCC subfamily, Ycf1p contains an N-terminal extension in addit...

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Autors principals: Paumi, Christian M., Chuk, Matthew, Chevelev, Igor, Stagljar, Igor, Michaelis, Susan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555997/
https://ncbi.nlm.nih.gov/pubmed/18667437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802569200
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