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Molecular Mechanisms Used by Tumors to Escape Immune Recognition: Immunogenetherapy and the Cell Biology of Major Histocompatibility Complex Class I

In this article, we explore the hypothesis that tumor cells can escape recognition by CD8(+) T cells via deficiencies in antigen processing and presentation. Aspects of the molecular and cellular biology of major histocompatibility complex class I are reviewed. Evidence for histology-specific molecu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Restifo, Nicholas P., Kawakami, Yutaka, Marincola, Franco, Shamamian, Peter, Taggarse, Akash, Esquivel, Fernando, Rosenberg, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555986/
https://ncbi.nlm.nih.gov/pubmed/8297900
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