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Steric and Electrostatic Effects in DNA Synthesis by the SOS-Induced DNA Polymerases II and IV of Escherichia coli

The SOS-induced DNA polymerases II and IV of Escherichia coli play important roles in processing lesions that occur in genomic DNA. Here we study how electrostatic and steric effects play different parts in influencing the efficiency and fidelity of DNA synthesis by these two enzymes. These effects...

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Autori principali: Silverman, Adam P., Jiang, Qingfei, Goodman, Myron F., Kool, Eric T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555966/
https://ncbi.nlm.nih.gov/pubmed/17988102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700851z
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