HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

The class II Histone deacetylase (HDAC), HDAC4, is expressed in a tissue-specific manner, and it represses differentiation of specific cell types. We demonstrate here that HDAC4 is expressed in the proliferative zone in small intestine and colon and that its expression is down-regulated during intes...

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Main Authors: Wilson, Andrew J., Byun, Do-Sun, Nasser, Shannon, Murray, Lucas B., Ayyanar, Kanyalakshmi, Arango, Diego, Figueroa, Maria, Melnick, Ari, Kao, Gary D., Augenlicht, Leonard H., Mariadason, John M.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2008
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555950/
https://ncbi.nlm.nih.gov/pubmed/18632985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0139
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