Vesicular stomatitis virus mutants resistant to defective-interfering particles accumulate stable 5'-terminal and fewer 3'-terminal mutations in a stepwise manner.

We have studied the evolution of sequences which include the RNA polymerase binding sites at the 5' and 3' termini of vesicular stomatitis virus mutants (Sdi-) resistant to defective-interfering particles. We observed a striking stepwise accumulation of stable base substitutions within the...

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Autores principales: O'Hara, P J, Horodyski, F M, Nichol, S T, Holland, J J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1984
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC255539/
https://ncbi.nlm.nih.gov/pubmed/6321763
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