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Use of a β1 Integrin-deficient Human T Cell to Identify β1 Integrin Cytoplasmic Domain Sequences Critical for Integrin Function

T cell activation rapidly and transiently regulates the functional activity of integrin receptors. Stimulation of CD3/T cell receptor, CD2 or CD28, as well as activation with phorbol esters, can induce within minutes an increase in β1 integrin-mediated adhesion of T cells to fibronectin. In this stu...

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Udgivet i:Mol Biol Cell
Principais autores: Romzek, Nadine C., Harris, Estelle S., Dell, Cheryl L., Skronek, Jeffrey, Hasse, Elizabeth, Reynolds, Pamela J., Hunt, Stephen W., Shimizu, Yoji
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 1998
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9763439/
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