Cargando...

A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4

The human CD45 gene encodes a protein–tyrosine phosphatase that exhibits differential isoform expression in resting and activated T cells due to alternative splicing of three variable exons. Previously, we have used biochemical methods to identify two regulatory proteins, hnRNP L and PSF, which cont...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Topp, Justin D., Jackson, Jason, Melton, Alexis A., Lynch, Kristen W.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553740/
https://ncbi.nlm.nih.gov/pubmed/18719244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1212008
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!