Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions

BACKGROUND: Epigenetics is the study of heritable changes in gene function that cannot be explained by changes in DNA sequence. One of the most commonly studied epigenetic alterations is cytosine methylation, which is a well recognized mechanism of epigenetic gene silencing and often occurs at tumor...

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Detalhes bibliográficos
Main Authors: Houseman, E Andres, Christensen, Brock C, Yeh, Ru-Fang, Marsit, Carmen J, Karagas, Margaret R, Wrensch, Margaret, Nelson, Heather H, Wiemels, Joseph, Zheng, Shichun, Wiencke, John K, Kelsey, Karl T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553421/
https://ncbi.nlm.nih.gov/pubmed/18782434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-365
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