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Phosphorylation of p130Cas initiates Rac activation and membrane ruffling

BACKGROUND: Non-receptor tyrosine kinases (NTKs) regulate physiological processes such as cell migration, differentiation, proliferation, and survival by interacting with and phosphorylating a large number of substrates simultaneously. This makes it difficult to attribute a particular biological eff...

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Bibliografiske detaljer
Main Authors: Sharma, Alok, Mayer, Bruce J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553404/
https://ncbi.nlm.nih.gov/pubmed/18793427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-50
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