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Monoclonal anti-hemagglutinin antibodies detect irreversible antigenic alterations that coincide with the acid activation of influenza virus A/PR/834-mediated hemolysis.

Exposure of influenza virus to an acidic environment, which is known to be required for viral fusion and hemolysis, has recently been shown to induce a conformational change in the hemagglutinin molecule. In the present study, we examined the effects of acid incubation on the antigenicity, biologica...

詳細記述

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書誌詳細
主要な著者: Yewdell, J W, Gerhard, W, Bachi, T
フォーマット: Artigo
言語:Inglês
出版事項: 1983
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC255340/
https://ncbi.nlm.nih.gov/pubmed/6193286
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