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Graded Hedgehog and Fibroblast Growth Factor Signaling Independently Regulate Pituitary Cell Fates and Help Establish the Pars Distalis and Pars Intermedia of the Zebrafish Adenohypophysis

The vertebrate adenohypophysis forms as a placode at the anterior margin of the neural plate, requiring both hedgehog (Hh) and fibroblast growth factor (Fgf) mediated cell-cell signaling for induction and survival of endocrine cell types. Using small molecule inhibitors to modulate signaling levels...

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Autors principals: Guner, Burcu, Ozacar, A. Tuba, Thomas, Jeanne E., Karlstrom, Rolf O.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553376/
https://ncbi.nlm.nih.gov/pubmed/18499750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0315
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