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Effects of Natalizumab Treatment on Foxp3+ T Regulatory Cells

BACKGROUND: Natalizumab, a monoclonal humanized antibody targeting the alpha-4 chain of very late activation antigen 4 (VLA-4) exerts impressive therapeutic effects in patients with relapsing-remitting multiple sclerosis. Our objective was to study impacts of Natalizumab therapy on Foxp3+ T regulato...

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Détails bibliographiques
Auteurs principaux: Stenner, Max-Philipp, Waschbisch, Anne, Buck, Dorothea, Doerck, Sebastian, Einsele, Hermann, Toyka, Klaus V., Wiendl, Heinz
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553177/
https://ncbi.nlm.nih.gov/pubmed/18836525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003319
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