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Metabolic innovations towards the human lineage

BACKGROUND: We describe a function-driven approach to the analysis of metabolism which takes into account the phylogenetic origin of biochemical reactions to reveal subtle lineage-specific metabolic innovations, undetectable by more traditional methods based on sequence comparison. The origins of re...

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Main Authors: Freilich, Shiri, Goldovsky, Leon, Ouzounis, Christos A, Thornton, Janet M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553087/
https://ncbi.nlm.nih.gov/pubmed/18782449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-247
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