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Polyomavirus large T antigen binds independently to multiple, unique regions on the viral genome.

To map the polyomavirus large T antigen binding sites on the viral genome we employed a quantitative immunoassay. Defined, radiolabeled fragments of the viral genome were reacted with crude nuclear extracts prepared from lytically infected mouse 3T6 cells, and the fragments bound by large T antigen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pomerantz, B J, Mueller, C R, Hassell, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6312084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.47.3.600-610.1983
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